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The text was composed in the name of the Shah in AH 1080/AD 1669-70. It is divided into sections on all aspects of health such as illnesses and their diagnoses, their cures, medicines, herbs, and unusually, sections on minerals, gemstones and talismanic symbols.
According to the official note on the opening page, it was given as waqf to Tabas Gilaki (a desert town between Kirman and Khurasan) by Amir 'Ali Naqi Khan, son of Muhammad Hasan Khan on muharram 1240/August-September 1824, and it bears his signature. A seal of his father on the same page shows that the manuscript had already been in his possession earlier, before 1819, when the father died, and so it must have been copied before that date. The same waqf text is written in shikasteh, most probably by the endower once in red and once in black on another two pages.
'Ali Naqi Khan of the Zangu'i Arab tribe was Governor of Tabas at the time and he is known to have accompanied Prince Muhammad Mirza (later Muhammad Shah) at his capture of Herat in 1833. (See M. Bamdad, Dictionary of National Biography of Iran, 1700-1900, vol. 2, 1966, p. 501).